The 15 Biggest Financial Institutions in the U.S. are Berkshire Hathaway, Omaha; Charlotte, North Carolina; JPMorgan Chase., N.Y. Bank of America; Wells Fargo, California’s San Francisco; Citigroup NY; American Express New York; MetLife, New York; Freddie Mac., Tysons Corner, Virginia; Goldman Sachs., N.Y.; The PNC Financial Services Group. Pittsburgh, Pennsylvania; Capital One. McLean, Virginia; State Farm. Bloomington, Illinois; Morgan Stanley. New York City, New York; Fannie Mae. Washington, D.C.; U.S. Bank. Minneapolis, Minnesota.